TIGRFAMs is a resource consisting of curated multiple sequence alignments, Hidden Markov Models (HMMs) for protein sequence classification, and associated information designed to support automated annotation of (mostly prokaryotic) proteins. Starting with release 10.0, TIGRFAMs models use HMMER3, which provides excellent search speed as well as exquisite search sensitivity.

To access the data below, click the format/version of your choice, then click the clipboard icon to copy the on-disk location. You can then paste it in your submission scripts to use in your analysis.

Back to top